Phospho-mTOR (Ser2448) Rabbit Polyclonal Antibody

Phospho-mTOR (Ser2448) Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab03727 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Phospho-mTOR (Ser2448) Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC

Reactivity

Human,Mouse,Pig

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

MTOR

Alternative Names

MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar

Gene ID

2475

SwissProt ID

P42345

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 289 kDa; Observed MW: 289 kDa

 

Background

An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

 

Research Area

Cell Biology

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