Recombinant Human ARSA (C-6His)

Recombinant Human ARSA (C-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890 SKU: PHH0103 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human ARSA (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.

Accession #

AAH14210.2

Host

Human Cells

Species

Human

Predicted Molecular Mass

52.9 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, pH 8.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA

 

Background

Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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