Phospho-Smad3 (Ser425) Rabbit Polyclonal Antibody

Phospho-Smad3 (Ser425) Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: APRab00823 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Phospho-Smad3 (Ser425) Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

SMAD3

Alternative Names

SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Gene ID

4088

SwissProt ID

P84022

 

Application

Dilution Ratio

WB: 1/500-1/1000 ELISA: 1/10000

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 58 kDa

 

Background

Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.

 

Research Area

Signal Transduction