USP13 Rabbit Polyclonal Antibody-Polyclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

USP13 Rabbit Polyclonal Antibody

Summary

Production Name	USP13 Rabbit Polyclonal Antibody
Description	Primary antibody
Host	Rabbit
Application	WB
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Polyclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	Affinity Chromatography

Immunogen

Gene Name	USP13
Alternative Names	Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13
Gene ID	8975
SwissProt ID	Q92995

Application

Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 97 kDa; Observed MW: 97 kDa

Background

Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

Research Area

Epigenetics and Nuclear Signaling