Wnt5a Rabbit Polyclonal Antibody

Wnt5a Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: APRab00192 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Wnt5a Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

WNT5A

Alternative Names

WNT5A; Protein Wnt-5a

Gene ID

7474

SwissProt ID

P41221

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 42 kDa; Observed MW: 42 kDa

 

Background

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.

 

Research Area

Neuroscience