Alternative Names
Aldo-Keto Reductase Family 1 Member C2; 3-Alpha-HSD3; Chlordecone Reductase Homolog HAKRD; Dihydrodiol Dehydrogenase 2; DD-2; DD2; Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; DD/BABP; Trans-1; 2-Dihydrobenzene-1; 2-Diol Dehydrogenase; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; AKR1C2; DDH2
Background
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Note
For Research Use Only , Not for Diagnostic Use.