PSPN Rabbit Polyclonal Antibody

PSPN Rabbit Polyclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: APRab00615 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

PSPN Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

PSPN

Alternative Names

PSPN; Persephin; PSP

Gene ID

5623

SwissProt ID

O60542

 

Application

Dilution Ratio

WB: 1/500-1/1000 ELISA: 1/10000

Molecular Weight

Calculated MW: 17 kDa; Observed MW: 17 kDa

 

Background

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.

 

Research Area

Neuroscience