DiMethyl-Histone H3 (Lys27) (5F6) Mouse Monoclonal Antibody

DiMethyl-Histone H3 (Lys27) (5F6) Mouse Monoclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: AMM03581 Category: Methyl Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

DiMethyl-Histone H3 (Lys27) (5F6) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,ICC/IF,IP

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Methylated

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

H3C1

Alternative Names

H3K27me2; H3 histone; HIST1H3A; Histone cluster 1; H3a

Gene ID

8350

SwissProt ID

P68431

 

Application

Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Molecular Weight

Calculated MW: 15 kDa; Observed MW: 15 kDa

 

Background

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

 

Research Area

Epigenetics and Nuclear Signaling