SIRT1 (2G10) Mouse Monoclonal Antibody

SIRT1 (2G10) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: AMM03526 Category: Mouse Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

SIRT1 (2G10) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG2b

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

SIRT1

Alternative Names

SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2

Gene ID

23411

SwissProt ID

Q96EB6

 

Application

Dilution Ratio

WB: 1/500-1/1000 IP: 1/20

Molecular Weight

Calculated MW: 82 kDa; Observed MW: 120 kDa

 

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.

 

Research Area

Cell Biology