HP1 gamma (5G10) Mouse Monoclonal Antibody

HP1 gamma (5G10) Mouse Monoclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: AMM03640 Category: Mouse Monoclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

HP1 gamma (5G10) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,IHC,IHC,ICC/IF,IP

Reactivity

Mouse,Human,Monkey,Hamster,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

CBX3

Alternative Names

CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Gene ID

11335

SwissProt ID

Q13185

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Molecular Weight

Calculated MW: 21 kDa; Observed MW: 21 kDa

 

Background

Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

 

Research Area

Epigenetics and Nuclear Signaling