SIRT2 (1D4) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

SIRT2 (1D4) Mouse Monoclonal Antibody

Summary

Production Name	SIRT2 (1D4) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	WB,ICC/IF
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG2b
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	SIRT2
Alternative Names	SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2
Gene ID	22933
SwissProt ID	Q8IXJ6

Application

Dilution Ratio	WB: 1/500-1/1000 IF: 1/50-1/200
Molecular Weight	Calculated MW: 43 kDa; Observed MW: 43 kDa

Background

Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.

Research Area

Epigenetics and Nuclear Signaling