Summary
| Production Name | ABCB5 (8D2) Mouse Monoclonal Antibody |
| Description | Primary antibody |
| Host | Mouse |
| Application | WB,ICC/IF |
| Reactivity | Human |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purified |
Immunogen
| Gene Name | ABCB5 |
| Alternative Names | ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5 |
| Gene ID | 340273 |
| SwissProt ID | Q2M3G0 |
Application
| Dilution Ratio | WB: 1/500-1/1000 IF: 1/50-1/200 |
| Molecular Weight | Calculated MW: 139 kDa; Observed MW: 90 kDa |
Background
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Research Area
Signal Transduction
