Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody

Summary

Production Name	Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	WB,ICC/IF
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Phosphorylated
Isotype	IgG2a
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	H2AX
Alternative Names	H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
Gene ID	3014
SwissProt ID	P16104

Application

Dilution Ratio	WB: 1/500-1/1000 IF: 1/50-1/200
Molecular Weight	Calculated MW: 15 kDa; Observed MW: 15 kDa

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Research Area

Epigenetics and Nuclear Signaling