Hsp27 (7E5) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

Hsp27 (7E5) Mouse Monoclonal Antibody

Summary

Production Name	Hsp27 (7E5) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	WB,ICC/IF
Reactivity	Human,Monkey

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	HSPB1
Alternative Names	HSPB1; HSP27; HSP28; Heat shock protein beta-1; HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27
Gene ID	3315
SwissProt ID	P04792

Application

Dilution Ratio	WB: 1/500-1/1000 IF: 1/50-1/200
Molecular Weight	Calculated MW: 23 kDa; Observed MW: 27 kDa

Background

Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway.

Research Area

Signal Transduction