LIN28A (9G2) Mouse Monoclonal Antibody

LIN28A (9G2) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: AMM03705 Category: Mouse Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

LIN28A (9G2) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

Purification

Ascitic Fluid

 

Immunogen

Gene Name

LIN28A

Alternative Names

CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.

Gene ID

79727

SwissProt ID

Q9H9Z2

 

Application

Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200

Molecular Weight

Calculated MW: 23 kDa; Observed MW: 23 kDa

 

Background

Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.

 

Research Area

Epigenetics and Nuclear Signaling