Oct-4 (3F5) Mouse Monoclonal Antibody

Oct-4 (3F5) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: AMM03422 Category: Mouse Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Oct-4 (3F5) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB

Reactivity

Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG2b

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

Pou5F1

Alternative Names

Oct-4 (3F5); Oct3; Oct4; Otf3; Otf4; NF-A3; Oct-3; Oct-4; Otf-3; Otf-4; Otf3g; Oct3/4; Oct-3/4; Otf3-rs7.

Gene ID

18999

SwissProt ID

P20263

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 38 kDa; Observed MW: 45 kDa

 

Background

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.

 

Research Area

Epigenetics and Nuclear Signaling