PTEN (7H2) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

PTEN (7H2) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200 SKU: AMM00755 Category: Mouse Monoclonal Antibody Tags: IHC, Unconjugated, Mouse, Cell Biology

Datasheet

Summary

Production Name	PTEN (7H2) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	IHC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	PTEN
Alternative Names	PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog
Gene ID	5728
SwissProt ID	P60484

Application

Dilution Ratio	IHC: 1/50-1/100
Molecular Weight	-

Background

Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.

Research Area

Cell Biology