MLKL (5E3) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

MLKL (5E3) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200 SKU: AMM00761 Category: Mouse Monoclonal Antibody Tags: IHC, Unconjugated, Mouse, Signal Transduction

Datasheet

Summary

Production Name	MLKL (5E3) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	IHC
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	MLKL
Alternative Names	MLKL
Gene ID	197259
SwissProt ID	Q8NB16

Application

Dilution Ratio	IHC: 1/50-1/100
Molecular Weight	-

Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Research Area

Signal Transduction