Recombinant Human DDR1 (C-Fc)

Recombinant Human DDR1 (C-Fc)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1980 SKU: PHH2454 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human DDR1 (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Epithelial discoidin domain-containing receptor 1 is produced by our Mammalian expression system and the target gene encoding Asp21-Thr416 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

Q08345-1

Host

Human cells

Species

Human

Predicted Molecular Mass

70.9 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 100mM NaCl, 0.05% Tween 80, pH 7.8.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; CD167a; DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE

 

Background

Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1 is a new potential target for drug discovery for human cancer and inflammatory disorders.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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