Recombinant Human HLA-A*0201 TP53 complex Protein (C-10His)-Target Proteins-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

Recombinant Human HLA-A*0201 TP53 complex Protein (C-10His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1680 SKU: PHH2407 Category: Target Proteins Tags: Human, Mammalian cells

Datasheet

Name	Recombinant Human HLA-A*0201 TP53 complex Protein (C-10His)
Purity	Greater than 95% as determined by reducing SDS-PAGE
Endotoxin level	<1 EU/µg as determined by LAL test.
Construction	Recombinant Human HLA-A*0201 TP53 complex Protein is produced by our Mammalian expression system and the target gene encoding (HMTEVVRHC)(R175H)&Ile21-Met119&Gly25-Ile308 (Ala269Val) is expressed with a 10His tag at the C-terminus.
Accession #	P61769&A0A140T913
Host	Human cells
Species	Human
Predicted Molecular Mass	49.1 KDa
Buffer	Lyophilized from a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 1mM EDTA, pH 7.4.
Form	Lyophilized
Shipping	The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Stability&Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Alternative Names

MHC, HLA-A*0201 TP53 complex Protein

Background

Cellular tumor antigen p53, is also known as TP 53, is the most frequently mutated gene across all cancers and encodes the tumor suppressor p53 protein. There is a neoepitope of TP53 which is p53R175H HMTEVVRHC. TP53 protein is degraded by the proteasome into peptides, some of which can be presented on the cell surface by human leukocyte antigen (HLA). The p53R175H /HLA-A*02:01 complex is a particularly attractive therapeutic target, shared by many cancer patients.

Note

For Research Use Only , Not for Diagnostic Use.