Recombinant Human EPO-R (C-Fc)

Recombinant Human EPO-R (C-Fc)

Size1:10μg price1:$76
Size2:50μg price2:$186
Size3:500μg price3:$1530 SKU: PHH2017 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human EPO-R (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Erythropoietin Receptor is produced by our Mammalian expression system and the target gene encoding Ala25-Pro250 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

P19235

Host

Human Cells

Species

Human

Predicted Molecular Mass

52 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 6% Trehalose, 4% Mannitol, 0.05% Tween 80, pH 7.5.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

EpoR; EPO-R; Erythropoietin R; erythropoietin receptor; MGC138358

 

Background

Erythropoietin (Epo), a glycoprotein produced primarily by the kidney, is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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