Alternative Names
COL21A1; collagen, type XXI, alpha 1; collagen alpha-1(XXI) chain; alpha 1 type XXI collagen; FP633; COLA1L; dJ708F5.1; dJ682J15.1; FLJ39125; FLJ44623; MGC26619; DKFZp564B052
Background
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interruptedhelices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, oneTSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in manytissues with the highest expression observed at the fetal stage. COL21A1 is stimulated byPDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type Icollagen; it may serve to maintain the integrity of the extracellular matrix.
Note
For Research Use Only , Not for Diagnostic Use.