Recombinant Mouse MARCO (N-8His)

Recombinant Mouse MARCO (N-8His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1240 SKU: PHM1134 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Mouse MARCO (N-8His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse Macrophage Receptor MARCO is produced by our Mammalian expression system and the target gene encoding Gln70-Ser518 is expressed with a 8His tag at the N-terminus.

Accession #

Q60754

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

46.2 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Macrophage receptor MARCO; Marco; Macrophage receptor with collagenous structure

 

Background

MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellular domain (ECD) that includes a stalk region, a collagenlike region, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and other determinants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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