Recombinant Human CD300a (C-6His)

Recombinant Human CD300a (C-6His)

Size1:10μg price1:$98
Size2:50μg price2:$248
Size3:500μg price3:$1680 SKU: PHH1093 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human CD300a (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Leukocyte Mono-Ig-like Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu18-Gln178 is expressed with a 6His tag at the C-terminus.

Accession #

Q9UGN4

Host

Human Cells

Species

Human

Predicted Molecular Mass

18.48 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

CMRF35-Like Molecule 8; CLM-8; CD300 Antigen-Like Family Member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1/IRC2; Immunoglobulin Superfamily Member 12; IgSF12; Inhibitory Receptor Protein 60; IRp60; NK Inhibitory Receptor; CD300a; CD300A; CMRF35H; IGSF12

 

Background

CD300A is a single-pass type I membrane protein that belongs to the CD300 family. CD300A consists of a 163 amino acid (aa) extracellular domain (ECD) with one Ig-like V- type domain, a 21 amino acid transmembrane segment, and a 98 amino acid cytoplasmic domain with tyrosine residues. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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