Summary
Performance
Immunogen
Application
Background
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain.,
Research Area
MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Chemokine;Dorso-ventral axis formation;Focal adhesion;Gap junction;Jak_STAT;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Neurotrophin;Regulates Actin and Cytoskeleton;Insulin_Receptor;GnRH;Pathways in cancer;Colorectal cancer;Renal cell carcinoma;Endometrial cancer;Glioma;Prostate cancer;Chronic myeloid leukemia;Acute myeloid leukemia;Non-small cell lung cancer;
