Recombinant Human OSMRB (C-6His)

Recombinant Human OSMRB (C-6His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1680 SKU: PHH0922 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human OSMRB (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Oncostatin-M-Specific Receptor Subunit Beta is produced by our Mammalian expression system and the target gene encoding Glu28-Ser739 is expressed with a 6His tag at the C-terminus.

Accession #

Q99650

Host

Human Cells

Species

Human

Predicted Molecular Mass

82.03 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Oncostatin-M-Specific Receptor Subunit Beta; Interleukin-31 Receptor Subunit Beta; IL-31 Receptor Subunit Beta; IL-31R Subunit Beta; IL-31R-Beta; IL-31RB; OSMR; OSMRB

 

Background

Oncostatin-M-Specific Receptor Subunit β (OSMRβ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRβ associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRβ associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRβ cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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