Phospho-JAK1 (Y1034 + Y1035) (14S9) Rabbit Monoclonal Antibody

Phospho-JAK1 (Y1034 + Y1035) (14S9) Rabbit Monoclonal Antibody

Size1:50μl Price1:$138
Size2:100μl Price2:$240
Size3:500μl Price3:$980 SKU: AMRe05929 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Phospho-JAK1 (Y1034 + Y1035) (14S9) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Phospho Antibody

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

JAK1

Alternative Names

JAK 1; JAK 1A; JAK 1B; JAK1; JAK1A; JAK1B; JTK3; historically have been referenced as Tyr1022 and Tyr1023 (Y1022 + Y1023);

Gene ID

3716

SwissProt ID

P23458

 

Application

Dilution Ratio

WB 1:500-1:2000

Molecular Weight

133kDa

 

Background

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558, PubMed:28111307, PubMed:32750333, PubMed:16239216). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529) as well as interleukin (IL)-10 receptor (PubMed:12133952). Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors (PubMed:16239216, PubMed:32750333).

 

Research Area

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