RGS6 (3A18) Rabbit Monoclonal Antibody

RGS6 (3A18) Rabbit Monoclonal Antibody

Size1:50μl Price1:$128
Size2:100μl Price2:$230
Size3:500μl Price3:$980
SKU: AMRe17100 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

RGS6 (3A18) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

RGS6

Alternative Names

GAP; RGS6; S914;

Gene ID

9628

SwissProt ID

P49758

 

Application

Dilution Ratio

WB 1:500-1:2000

Molecular Weight

54kDa

 

Background

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/Gbeta5 dimer. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509).

 

Research Area