Alpha Fodrin (15V11) Rabbit Monoclonal Antibody

Alpha Fodrin (15V11) Rabbit Monoclonal Antibody

Size1:50μl Price1:$128
Size2:100μl Price2:$230
Size3:500μl Price3:$980
SKU: AMRe06793 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Alpha Fodrin (15V11) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Purification

Affinity purification

 

Immunogen

Gene Name

SPTAN1

Alternative Names

Alpha II Spectrin; EIEE5; Fodrin alpha chain; NEAS; SPECA; Spectrin; Spna2; SPTAN1;

Gene ID

6709

SwissProt ID

Q13813

 

Application

Dilution Ratio

WB 1:1000-1:5000

Molecular Weight

285kDa

 

Background

Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits (1). This protein is important for maintaining normal membrane structure and supporting cell surface protein function (1). Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.

 

Research Area