TIEG-1/2 Rabbit Polyclonal Antibody

TIEG-1/2 Rabbit Polyclonal Antibody

Size1:50μl Price1:$118
Size2:100μl Price2:$220
Size3:500μl Price3:$980 SKU: APRab18926 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

TIEG-1/2 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

IHC,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

KLF10/11

Alternative Names

KLF10; TIEG; TIEG1; Krueppel-like factor 10; EGR-alpha; Transforming growth factor-beta-inducible early growth response protein 1; TGFB-inducible early growth response protein 1; TIEG-1; KLF11; FKLF; TIEG2; Krueppel-like factor 11; Transfor

Gene ID

7071/8462

SwissProt ID

Q13118/O14901

 

Application

Dilution Ratio

IHC 1:100-1:300 ELISA: 1:5000

Molecular Weight

 

Background

This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],function:Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.,induction:By TGF-beta.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

 

Research Area

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