Bc10 Rabbit Polyclonal Antibody

Bc10 Rabbit Polyclonal Antibody

Size1:50μl Price1:$118
Size2:100μl Price2:$220
Size3:500μl Price3:$980
SKU: APRab07483 Category: Polyclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Bc10 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

IF,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

BLCAP

Alternative Names

BLCAP; BC10; Bladder cancer-associated protein; Bladder cancer 10 kDa protein; Bc10

Gene ID

10904

SwissProt ID

P62952

 

Application

Dilution Ratio

IF 1:200-1:1000. ELISA: 1:40000.

Molecular Weight

 

Background

This gene encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. This gene is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID:4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein. [provided by RefSeq, Nov 2015],similarity:Belongs to the BLCAP family.,tissue specificity:Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas.,

 

Research Area