XPD Rabbit Monoclonal antibody

XPD Rabbit Monoclonal antibody

Size1:50μL Price1:$158 $99
Size2:100μL Price2:$288 $180
Application:WB,ICC/IF
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:ERCC2 SKU: AMRe02779 Category: Rabbit Monoclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

XPD Rabbit Monoclonal antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

ERCC2

Alternative Names

BTF2 p80; COFS2; CXPD; EM9; ERCC2; MAG; TFIIH p80; TTD; XPD; XPDC

Gene ID

2068

SwissProt ID

P18074

 

Application

Dilution Ratio

WB: 1:500-1:1000 IF: 1:50-1:200

Molecular Weight

Calculated MW: 87 kDa; Observed MW: 80 kDa

 

Background

ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity.

 

Research Area

Epigenetics and Nuclear Signaling

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