KDM1A Rabbit Monoclonal antibody

KDM1A Rabbit Monoclonal antibody

Size1:50μL Price1:$188 $99
Size2:100μL Price2:$338 $180
Application:WB,ICC/IF,IP
Reactivity:Human,Hamster,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:KDM1A SKU: AMRe02190 Category: Rabbit Monoclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

KDM1A Rabbit Monoclonal antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,ICC/IF,IP

Reactivity

Human,Hamster,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

KDM1A

Alternative Names

KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

Gene ID

23028

SwissProt ID

O60341

 

Application

Dilution Ratio

WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20

Molecular Weight

Calculated MW: 93 kDa; Observed MW: 110 kDa

 

Background

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

 

Research Area

Epigenetics and Nuclear Signaling

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