LIN28A (2C1) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

LIN28A (2C1) Mouse Monoclonal Antibody

Summary

Production Name	LIN28A (2C1) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	WB
Reactivity	Human,Mouse

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG2a
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	LIN28A
Alternative Names	CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; Zinc finger CCHC domain-containing protein 1.
Gene ID	79727
SwissProt ID	Q9H9Z2

Application

Dilution Ratio	WB: 1/500-1/1000
Molecular Weight	Calculated MW: 23 kDa; Observed MW: 26 kDa

Background

Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.

Research Area

Epigenetics and Nuclear Signaling