PTEN (7H2) Mouse Monoclonal Antibody- aEnkiLife

PTEN (7H2) Mouse Monoclonal Antibody

Size1:50μL Price1:$150
Size2:100μL Price2:$280
Size3:200μL Price3:$520
Application:IHC-P
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PTEN SKU: AMM00755 Category: Mouse Monoclonal Antibody Tags: Cell Biology, Mouse, Unconjugated, IHC, Human

Datasheet Copy

Summary

Production Name	PTEN (7H2) Mouse Monoclonal Antibody
Description	Mouse Monoclonal Antibody
Host	Mouse
Application	IHC-P
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purification

Immunogen

Gene Name	PTEN
Alternative Names	PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog
Gene ID	5728
SwissProt ID	P60484

Application

Dilution Ratio	IHC: 1:50-1:100
Molecular Weight	-

Background

Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.

Research Area

Cell Biology