Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse Monoclonal Antibody

Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse Monoclonal Antibody

Size1:50μL Price1:$168
Size2:100μL Price2:$300
Size3:200μL Price3:$520
Application:IHC-P
Reactivity:Human,Rat,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:MAPK1/MAPK3 SKU: AMM00747 Category: Mouse Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse Monoclonal Antibody

Description

Mouse Monoclonal Antibody

Host

Mouse

Application

IHC-P

Reactivity

Human,Rat,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purification

 

Immunogen

Gene Name

MAPK1/MAPK3

Alternative Names

MAPK1/MAPK3

Gene ID

5595/5594

SwissProt ID

P27361/P28482

 

Application

Dilution Ratio

IHC: 1:50-1:100

Molecular Weight

-

 

Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

 

Research Area

Cell Biology

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