Recombinant Mouse HGF (C-6His)

Recombinant Mouse HGF (C-6His)

Size1:10μg price1:$136
Size2:50μg price2:$378
Size3:500μg price3:$1890 SKU: PHM1923 Category: Cytokines Tags: ,

Datasheet

Name

Recombinant Mouse HGF (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<0.01 EU/µg as determined by LAL test.

Construction

Recombinant Mouse Hepatocyte Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln33-/xadLeu728 is expressed with a 6His tag at the C-terminus.

Accession #

Q08048

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

53.5&26.9 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Hepatopoietin-A; Scatter factor; SF; deafness; autosomal recessive 39; DFNB39; F-TCF; hepatocyte growth factor

 

Background

HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60/xa0kDa alpha /xa0and 30 kDa beta /xa0chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. /xa0It can also alter epithelium morphology by the induction of nectin‑1 alpha /xa0ectodomain shedding, an adhesion protein component of adherens junctions/xa0.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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