Recombinant Human Siglec-6 (C-Fc)

Recombinant Human Siglec-6 (C-Fc)

Size1:10μg price1:$66
Size2:50μg price2:$186
Size3:500μg price3:$1530 SKU: PHH2343 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human Siglec-6 (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Sialic acid-binding Ig-like lectin 6 is produced by our Mammalian expression system and the target gene encoding Glu27-Val331 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

O43699-3

Host

Human Cells

Species

Human

Predicted Molecular Mass

60.6 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.5.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec6; Siglec-6

 

Background

Siglec-6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. Siglec-6 mediates sialic-acid dependent binding to cells. Siglec-6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Siglec-6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Siglec-6 is found on B cells and in placenta, and would seem to have a restricted specificity for the sialyl Tn antigen.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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