CHK2_HUMAN O96017
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UniProt:O96017
Recommended name：Serine/threonine-protein kinase Chk2
EC number：EC:2.7.11.1
Alternative names：(CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Cleaved into：
GeneID：11200
Gene names (primary )：CHEK2
Gene names (synonym )：CDS1 CHK2 RAD53
Gene names (ORF )：
Length：543
Mass：60915
Sequence：MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
Tissue specificity：High expression is found in testis, spleen, colon and peripheral blood leukocytes. Low expression is found in other tissues.
Induction：
Developmental stage：
Protein families：Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CHK2 subfamily