ASIC1_RAT P55926
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UniProt:P55926
Recommended name：Acid-sensing ion channel 1 1 Publication
EC number：
Alternative names：Acid-sensing ionic channel 1 Publication (ASIC 1 Publication) Amiloride-sensitive cation channel 2, neuronal Brain sodium channel 2 Imported
Cleaved into：
GeneID：
Gene names (primary )：Asic1
Gene names (synonym )：Accn2 Imported, Bnac2 Imported
Gene names (ORF )：
Length：526
Mass：59,641
Sequence：MELKTEEEEVGGVQPVSIQAFASSSTLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQYYFCYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEACSAEDFKVVFTRYGKCYTFNSGQDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLIYLPSPWGTCNAVTMDSDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHRLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPCESLRGHPAGMTYAANILPHHPARGTFEDFTC
Tissue specificity：Expressed in dorsal root ganglia and sciatic nerve (at protein level) (PubMed:11842212). Widely distributed throughout the brain. Expressed in olfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. Diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus (PubMed:9360943). 2 s
Induction：Expressed exclusively in trigeminal ganglion and dorsal root ganglion. 1 Publication
Developmental stage：Expressed only in dorsal root ganglion (DRG). 1
Protein families：amiloride-sensitive sodium channel (TC 1.A.6) family