TMPS4_HUMAN Q9NRS4
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UniProt:Q9NRS4
Recommended name：Transmembrane protease serine 4
EC number：EC:3.4.21.-
Alternative names：(Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2)
Cleaved into：Transmembrane protease serine 4 catalytic chain
GeneID：56649
Gene names (primary )：TMPRSS4
Gene names (synonym )：TMPRSS3
Gene names (ORF )：UNQ776/PRO1570
Length：437
Mass：48246
Sequence：MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL
Tissue specificity：High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract (PubMed:10825129). Coexpressed with ACE2 within mature enterocytes (PubMed:32404436). {ECO:0000269|PubMed:10825129, ECO:0000269|PubMed:32404436}.
Induction：
Developmental stage：
Protein families：Peptidase S1 family