BNIP-3 Rabbit Polyclonal Antibody

BNIP-3 Rabbit Polyclonal Antibody

Size1:50μL Price1:$118
Size2:100μL Price2:$220
Size3:500μL Price3:$980
Application:WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA
Reactivity:Human,Rat,Mouse
Conjugate:Unconjugated
Gene Name:BNIP3 SKU: APRab07619 Category: Polyclonal Antibody Tags: , , , , , , , , , , ,

Datasheet

Summary

Production Name

BNIP-3 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

Reactivity

Human,Rat,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

BNIP3

Alternative Names

BNIP3; NIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

Gene ID

664

SwissProt ID

Q12983

 

Application

Dilution Ratio

WB 1:500-1:2000, IHC-P 1:100-300, ELISA 1:20000, IF-P/IF-F/ICC/IF 1:50-200

Molecular Weight

22kDa

 

Background

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],function:Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.,similarity:Belongs to the NIP3 family.,subcellular location:Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope.,subunit:Homodimer. Binds to BCL2. Interacts with BNIP3L. Also can interact with adenovirus E1B 19 kDa protein or Epstein-Barr virus BHRF1.,

 

Research Area

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