Securin (6K10) Rabbit Monoclonal Antibody

Securin (6K10) Rabbit Monoclonal Antibody

Size1:50μl Price1:$138
Size2:100μl Price2:$240
Size3:500μl Price3:$980
SKU: AMRe17701 Category: Rabbit Monoclonal Antibody Tags: , ,

Datasheet

Summary

Production Name

Securin (6K10) Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal Antibody

Host

Rabbit

Application

WB

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

Purification

Affinity purification

 

Immunogen

Gene Name

Alternative Names

Cut2; EAP1; hPTTG; Pds1; PTTG; PTTG1; Pttg3; Securin; TUTR1;

Gene ID

SwissProt ID

O95997/Q6IAL9

 

Application

Dilution Ratio

WB: 1:1000-1:5000

Molecular Weight

22kDa

 

Background

Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.

 

Research Area