Summary
Performance
Immunogen
Application
Background
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2. Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity).
Research Area