Recombinant Human SGSH (C-6His)

Recombinant Human SGSH (C-6His)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2350
SKU: PHH1578 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human SGSH (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human N-Sulphoglucosamine Sulphohydrolase is produced by our Mammalian expression system and the target gene encoding Arg21-Leu502 is expressed with a 6His tag at the C-terminus.

Accession #

P51688

Host

Human Cells

Species

Human

Predicted Molecular Mass

55.72 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM CaCl2, 10% Glycerol, pH 7.5.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

N-Sulphoglucosamine Sulphohydrolase; Sulfoglucosamine Sulfamidase; Sulphamidase; SGSH; HSS

 

Background

N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

 

Note

For Research Use Only , Not for Diagnostic Use.