Growth Hormone Receptor Rabbit Monoclonal Antibody

Growth Hormone Receptor Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe02062 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

Growth Hormone Receptor Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

GHR

Alternative Names

GHR; Growth hormone receptor; GH receptor; Somatotropin receptor

Gene ID

2690

SwissProt ID

P10912

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 72 kDa; Observed MW: 120 kDa

 

Background

Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

 

Research Area

Signal Transduction

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