VCAM1 Rabbit Monoclonal Antibody

VCAM1 Rabbit Monoclonal Antibody

Size1:50μl Price1:$158
Size2:100μl Price2:$288
Size3:500μl Price3:$1200 SKU: AMRe01575 Category: Rabbit Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

VCAM1 Rabbit Monoclonal Antibody

Description

Recombinant Rabbit Monoclonal antibody

Host

Rabbit

Application

WB

Reactivity

Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purified

 

Immunogen

Gene Name

Vcam1

Alternative Names

VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106

Gene ID

22329

SwissProt ID

P29533

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 81 kDa; Observed MW: 100 kDa

 

Background

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

 

Research Area

Signal Transduction

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