Summary
Production Name | ATF5 Rabbit Monoclonal Antibody |
Description | Rabbit Monoclonal antibody |
Host | Rabbit |
Application | WB,IHC-P,IP |
Reactivity | Human,Mouse,Rat |
Performance
Conjugation | Unconjugated |
Modification | Unmodified |
Isotype | IgG |
Clonality | Monoclonal Antibody |
Form | Liquid |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Purification | Affinity Purification |
Immunogen
Gene Name | ATF5 |
Alternative Names | ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx |
Gene ID | 22809 |
SwissProt ID | Q9Y2D1 |
Application
Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 IP: 1:20 |
Molecular Weight | Calculated MW: 31 kDa; Observed MW: 31 kDa |
Background
ATF5 or Activating transcription factor 5, binds to cAMP inducible promoters and is involved in gene transcription. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF5 plays a role in inhibition of nerve growth factor induced neuronal outgrowth and regulation of neurogenesis.
Research Area
Epigenetics and Nuclear Signaling