Summary
| Production Name | PI3 Kinase p55 gamma Rabbit Monoclonal Antibody |
| Description | Rabbit Monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC-P,ICC/IF |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity Chromatography |
Immunogen
| Gene Name | PIK3R3 |
| Alternative Names | GRB1; P85A; PI3-kinase p85-alpha subunit; PI3K; PI3K p85-alpha; P55G; PI3-kinase p85-gamma subunit; PI3K p85-gamma |
| Gene ID | 8503 |
| SwissProt ID | Q92569 |
Application
| Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 |
| Molecular Weight | Calculated MW: 54 kDa; Observed MW: 54 kDa |
Background
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
Research Area
Signal Transduction
