Recombinant Mouse MMP-12 (C-6His)

Recombinant Mouse MMP-12 (C-6His)

Size1:10μg price1:$168
Size2:50μg price2:$465
Size3:500μg price3:$2350
SKU: PHM1126 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Mouse MMP-12 (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Mouse Matrix Metalloproteinase 12 is produced by our Mammalian expression system and the target gene encoding Ala29-Cys473 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by APMA for an activated form.

Accession #

P34960

Host

Human Cells

Species

Mouse

Predicted Molecular Mass

53 KDa

Buffer

Supplied as a 0.2 μm filtered solution of 20mM PB, 500mM NaCl,0.01%Tween80, 1mM EDTA, 50% Glycerol, pH6.0.

Form

Liquid

Shipping

The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

 

 

 

Alternative Names

Macrophage metalloelastase; MME; Matrix metalloproteinase-12; MMP-12; Mmp12; Mme; Mmel

 

Background

Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1 site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

 

Note

For Research Use Only , Not for Diagnostic Use.